Nail matrix melanoma: consecutive cases in a general practice

Nail matrix melanoma: consecutive cases in a general practice

Nail matrix melanoma, otherwise known as subungual melanoma, is unique in that the actual primary cutaneous melanoma is occult, being covered by the nail plate and the proximal nail fold. Fortunately, the concealed melanoma may produce melanin, which then appears as longitudinal pigmentation in the nail plate. Thus melanin-producing nail matrix melanoma has a distinctive ‘signature’ to the info...

Nodular melanoma: five consecutive cases in a general practice with polarized and non-polarized dermatoscopy and dermatopathology

BACKGROUND The incidence of nodular melanoma (NM) has been consistently described as at least 10-15% of total melanomas for over 15 years despite advances in diagnostic algorithms and medical technology. NMs are strongly correlated with faster rates of growth and poorer prognosis and thus provide clinicians with a challenge for early recognition. OBJECTIVE To evaluate diagnostic clues of cons...

A review of 508 consecutive patients seen in general practice.

Choroidal nevus transformation into melanoma: analysis of 2514 consecutive cases.

OBJECTIVE To determine features that are predictive of growth of choroidal nevi into melanoma. METHODS This was a retrospective medical record review of 2514 consecutive eyes; Kaplan-Meier estimates and Cox regression analyses were used. RESULTS The median tumor basal diameter was 5.0 mm and thickness was 1.5 mm. Nevus growth into melanoma occurred in 2%, 9%, and 13% of eyes at 1, 5, and 10...

Two cases of neurosyphilis in general practice.

patients and myself suggest that mebrophenhydramine is superior to others currently available. This is based on the speed and completeness of response in a large proportion of allergic patients, the scope of the conditions satisfactorily treated and the small incidence of side effects. The results obtained in the four patients with neurodermatitis warrants a fuller investigation of the treatmen...